Brainy people

After reading about Terry Gilliam’s views on one of his old gang, I came across this moving article from a couple of years ago about two others — Terry Jones and Michael Palin discussing dementia.

Terry Jones: ‘I’ve got dementia. My frontal lobe has absconded’
The pair still regularly have lunch together. “We chat – well, I chat,” added Palin. “But when the meal is over he makes it clear he has to move. He has to get to the next thing on his agenda and he just puts his head down and goes. I have never felt discomfited in his presence, however. There is no embarrassment. He doesn’t shout or show his bottom.”

Only taxis cause problems. “He always wants to give directions and he hates traffic,” said Sally. “That is nothing new in a sense. He always knew a better way and would always let the taxi driver know that very early on in the journey.” At this point, Jones nods vigorously.

I wonder what he’d make of this new restaurant.

The Restaurant of Mistaken Orders
The servers at The Restaurant of Mistaken Orders, a series of pop-up restaurants in Tokyo, are all living with dementia, which means that you might not receive what you ordered.

[…]

“It’s OK if my order was wrong. It tastes so good anyway.” We hope this feeling of openness and understanding will spread across Japan and through the world.

And then coincidentally I read this, about another hero to many in declining health — Linda Ronstadt on living with Parkinson’s.

Linda Ronstadt has found another voice
In the documentary, you say, “I can sing in my mind, but I can’t do it physically.” That sounds either comforting or excruciating.

Well, it’s a little frustrating when my family comes over from Arizona, because we would all sing together. That way we don’t have to talk about politics. It makes for harmonious—I don’t mean the pun—relations. But I can’t do that anymore, so I just invite the ones who are Democrats.

I don’t know much about Linda, but I adore her singing on Philip Glass’s Songs From Liquid Days album. (She’s on ‘Freezing’, with words by Suzanne Vega, and ‘Forgetting’, with words by Laurie Anderson.) Her voice is so just strong and pure, it cuts right through you. I was looking for something for something on YouTube from that album, but all I could find was this clip. Remember Kenny Everett and Hot Gossip?

Anyway, where was I? Ah yes. They say that brains are the most complicated things in the universe. You’d never be able to do something as crass as grow one in a lab, right?

Cerebral organoids are becoming more brainlike
At what point does a mass of nerve cells growing in a laboratory Petri dish become a brain? That question was first raised seriously in 2013 by the work of Madeline Lancaster, a developmental biologist at the Medical Research Council’s Laboratory of Molecular Biology, in Cambridge, Britain. That year Dr Lancaster and her colleagues grew the first human-derived “cerebral organoid”.

[…]

Since then, Dr Lancaster’s work has advanced by leaps and bounds. In March, for example, she announced that her organoids, when they are connected to the spinal cord and back-muscle of a mouse, could make that muscle twitch.

All done in the best possible taste.